Experimental Oncology

Faculty Members are involved in basic scientific research and translational (bench-to-bedside) research. Research interests include:


  1. Molecular analysis of breast cancer, brain tumours, melanoma, pediatric cancers and blood cancers
  2. Mechanisms underlying the repair of DNA damage caused by ionizing radiation and chemotherapeutic drugs
  3. Cell adhesion, cell migration and metastatic spread
  4. Epigenetics of cancer
  5. Tumour suppressor genes
  6. Tumour targeting viruses as cancer therapeutic agents
  7. Computational biology approaches to drug discovery
  8. Cell cycle regulation
  9. Membrane transporters and their role in drug transport and resistance

Possible areas of graduate research include:

Dr. Kristi Baker

Anti-tumor immunity; genetic instability; colorectal cancer

Dr. Gordon Chan

Mitotic cell cycle checkpoint and cancer

Dr. YangXin Fu
Signaling pathways and gene regulation in ovarian cancer and therapeutics
Dr. Roseline Godbout
Cancer as a developmental disease; retinoblastoma; brain tumors
Dr. Michael Hendzel
Nuclear components; DNA damage response; chromatin-based epigenetic mechanisms
Dr. Mary Hitt
Oncolytic viruses; adenovirus replication; gene regulation; RNA interference; gene therapy
Dr. John Lewis
Translational prostate cancer research; nanoparticles, novel therapeutics, in vivo imaging
Dr. David Murray
DNA repair in the response to anti-cancer agents; prediction of patient response to therapy
Dr. Manijeh Pasdar
Molecular mechanisms of adhesion-mediated signaling during cell growth and oncogenesis
Dr. Jack Tuszynski
Computational biophysics; rational drug design; pharmacokinetics
Dr. Alan Underhill
Transcription factors in melanoma; gene regulation & epigenetics
Dr. Michael Weinfeld
Detection and repair of DNA damage
Dr. Frank Wuest
Probe development for molecular imaging of cancer
Dr. Armin Gamper
DNA damage response: radiation biology